Description

4-(Phenylsulfonyl)Benzonitrile is a versatile aromatic sulfone derivative with a nitrile functional group, serving as a critical building block in advanced organic synthesis. Its unique structure makes it a valuable intermediate for creating complex molecules with specific electronic and steric properties. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and enzyme inhibitors.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging its sulfone moiety for biological activity.
• Material Science Research: Serves as a monomer or building block for high-performance polymers, liquid crystals, and organic electronic materials.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, cyanation processes, and as a scaffold for constructing complex heterocyclic compounds.
• Dye & Pigment Manufacturing: Intermediate for producing specialized dyes and pigments with enhanced lightfastness and chemical stability.

Basic Information

Product Name	4-(Phenylsulfonyl)Benzonitrile
CAS No.	28525-13-5
Molecular Formula	C13H9NO2S
Molecular Weight	243.28 g/mol
Synonyms	4-(Benzenesulfonyl)benzonitrile; p-(Phenylsulfonyl)benzonitrile; [1,1'-Biphenyl]-4-carbonitrile, 4'-sulfonyl-; Benzonitrile, 4-(phenylsulfonyl)-; 4-Phenylsulfonylbenzonitrile; NSC 403119; 4-(Phenylsulphonyl)benzonitrile
EINECS	Contact for details

Quality Control

Our 4-(Phenylsulfonyl)Benzonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) are provided with every shipment, documenting compliance with agreed specifications. We support cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and moisture. The container should be kept tightly sealed when not in use to prevent contamination and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	142 - 146 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.