Description

p-Methylcinnamonitrile is a versatile aromatic nitrile derivative, serving as a key intermediate in advanced organic synthesis. Its value lies in its reactive cyano group and conjugated system, enabling the construction of complex molecular frameworks for high-value applications. This compound is essential for R&D chemists and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in developing molecules with anti-inflammatory or central nervous system activity.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its structure contributes to the biological activity of the final product.
• Liquid Crystal & OLED Materials: Acts as a precursor in the manufacture of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs).
• Fine Chemical Production: Employed in the synthesis of dyes, pigments, and other performance chemicals requiring specific aromatic nitrile functionalities.
• Cross-Coupling Reactions: Serves as a valuable substrate in palladium-catalyzed reactions, such as Suzuki or Heck couplings, for creating complex biaryl structures.
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D labs for exploring new synthetic pathways and material properties.

Basic Information

Product Name	p-Methylcinnamonitrile
CAS No.	28446-70-0
Molecular Formula	C10H9N
Molecular Weight	143.19 g/mol
Synonyms	4-Methylcinnamonitrile; (E)-3-(4-Methylphenyl)-2-propenenitrile; 3-(p-Tolyl)acrylonitrile; trans-4-Methylcinnamonitrile; p-Tolylacrylonitrile; 2-Propenenitrile, 3-(4-methylphenyl)-; (E)-3-(4-Methylphenyl)acrylonitrile; 4-Methyl-trans-cinnamnitrile
EINECS	Contact for details

Quality Control

Our p-Methylcinnamonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. For customers with specific regulatory needs, we can support documentation for cGMP, ISO, or REACH compliance upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	85 - 89 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.