Description

(25R)-3β,16-Dihydroxyspirost-5-En-11-One CAS NO 28426-01-9 is a high-purity steroidal sapogenin derivative, a key intermediate in the synthesis of complex bioactive molecules. Its value lies in providing a structurally defined, optically pure scaffold for advanced pharmaceutical research and development. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors, particularly those focused on steroid-based therapeutics and novel drug discovery.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of steroidal drugs and active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new therapeutic agents.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Biochemical Research: Employed in studies investigating steroid biosynthesis pathways, enzyme inhibition, and receptor binding.
• Fine Chemical Synthesis: A versatile starting material for the custom synthesis of specialized steroidal compounds for various industrial applications.

Basic Information

Product Name	(25R)-3β,16-Dihydroxyspirost-5-En-11-One
CAS No.	28426-01-9
Molecular Formula	C27H40O5
Molecular Weight	444.60 g/mol
Synonyms	(25R)-Spirost-5-ene-3β,11,16-triol, 11-one; 3β,16-Dihydroxy-5α-spirost-11-one; 11-Ketotigogenin; Tigogenone; (25R)-3β,16α-Dihydroxy-5α-spirostan-11-one; 5α-Spirostan-3β,16-diol-11-one
EINECS	Contact for details

Quality Control

Our (25R)-3β,16-Dihydroxyspirost-5-En-11-One is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and comprehensive identification tests. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when required.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (25R)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.