Description

(22S,25R)-3β-Hydroxy-5α-Spirostan-23-One is a high-purity steroidal sapogenin derivative, a key intermediate in the synthesis of complex bioactive molecules. Its defined stereochemistry at the 22S and 25R positions makes it a critical chiral building block for pharmaceutical research and development. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel steroid-based therapeutics and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial chiral precursor for the synthesis of steroidal drugs, including certain classes of hormones, anti-inflammatory agents, and cardiac glycosides.
• Agrochemical Research: Used in the development of novel plant growth regulators and eco-friendly pesticides with steroidal frameworks.
• Fine Chemical Synthesis: Serves as a versatile starting material for synthesizing complex natural products and specialty chemicals requiring the spirostan skeleton.
• Biochemical Research: Employed as a reference standard or probe in studies investigating sterol biosynthesis and metabolism pathways.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	(22S,25R)-3β-Hydroxy-5α-Spirostan-23-One
CAS No.	28404-66-2
Molecular Formula	C27H42O4
Molecular Weight	430.62 g/mol
Synonyms	23-Oxotigogenin; (22S,25R)-Spirostan-3β-ol-23-one; 3β-Hydroxy-5α-spirostan-23-one; Tigogenone; Tigogen-23-one; 23-Ketotigogenin; (25R)-3β-Hydroxyspirostan-23-one
EINECS	Contact for details

Quality Control

Our (22S,25R)-3β-Hydroxy-5α-Spirostan-23-One is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical and isomeric purity and identity confirmation. Certificates of Analysis (COA) detailing all test results are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Isomeric Purity (HPLC)	≥ 99.0% (22S,25R)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.