Description

5-Methoxy-Isobenzofuran-1,3-Dione is a versatile and high-purity organic intermediate of significant interest in advanced chemical synthesis. Its unique heterocyclic structure, featuring a fused furanone ring, makes it a valuable precursor for constructing complex molecules in pharmaceutical and agrochemical research. This compound is particularly sought after by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), specialty dyes, and performance materials who require reliable, high-quality building blocks.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those with fused heterocyclic scaffolds for therapeutic applications.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that require specific isobenzofuranone motifs.
• Organic Synthesis Building Block: Serves as a versatile precursor for Diels-Alder reactions, nucleophilic substitutions, and ring-opening transformations to create complex organic architectures.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized colorants and functional dyes due to its electron-rich aromatic system.
• Material Science Research: Investigated as a monomer or cross-linking agent for developing polymers with specific thermal or optical properties.
• Academic & Industrial R&D: A critical reagent for methodological studies and discovery chemistry in university and corporate laboratories worldwide.

Basic Information

Product Name	5-Methoxy-Isobenzofuran-1,3-Dione
CAS No.	28281-76-7
Molecular Formula	C9H6O4
Molecular Weight	178.14 g/mol
Synonyms	5-Methoxyphthalic Anhydride; 5-Methoxy-1,3-isobenzofurandione; 5-Methoxy-1,3-dihydro-2-benzofuran-1,3-dione; 5-Methoxybenzofuran-1,3-dione; 5-Methoxy-1,3-dioxoisobenzofuran; 5-Methoxyisobenzofuran-1,3-dione; 5-Methoxypththalic anhydride; 28281-76-7
EINECS	Contact for details

Quality Control

Our 5-Methoxy-Isobenzofuran-1,3-Dione is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.