Description

2,8-Dichloro-1,5-Naphthyridine is a halogenated naphthyridine derivative that serves as a versatile and high-value synthetic intermediate. Its molecular structure makes it a critical building block for constructing complex heterocyclic systems used in advanced material science and pharmaceutical development. This compound is primarily sought by R&D chemists and process development scientists in the agrochemical and pharmaceutical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other biological pathways.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, leveraging its heterocyclic core for bioactivity.
• Material Science Research: Serves as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specialized heterocyclic chemistry.

Basic Information

Product Name	2,8-Dichloro-1,5-Naphthyridine
CAS No.	28252-76-8
Molecular Formula	C8H4Cl2N2
Molecular Weight	199.04 g/mol
Synonyms	1,5-Naphthyridine, 2,8-dichloro-; 2,8-Dichloro-1,5-naphthyridine; 2,8-Dichloro-1,5-diazanaphthalene; 1,5-Diazanaphthalene, 2,8-dichloro-; Dichloronaphthyridine; 2,8-DCN; 28252-76-8
EINECS	Contact for details

Quality Control

Our 2,8-Dichloro-1,5-Naphthyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.