Description

cis-2-Aminomethyl-1-Cyclohexanol Hydrochloride is a high-purity, functionalized cyclohexane derivative that serves as a versatile chiral building block and intermediate in advanced organic synthesis. Its value lies in the combination of a primary amine group and a hydroxyl group on the cyclohexane ring, which can be selectively modified for complex molecule construction. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs), chiral ligands, and specialty polymers.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, including central nervous system (CNS) agents and receptor modulators.
• Asymmetric Catalysis: Used in the preparation of chiral ligands and catalysts for enantioselective synthesis.
• Peptidomimetics & Bioactive Molecules: The aminomethyl and hydroxyl functionalities make it a valuable scaffold for designing peptide analogs and other bioactive compounds.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for producing specialty polyamides, polyurethanes, or epoxy resins with tailored properties.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, or plant growth regulators.
• Chemical Research & Development: Serves as a standard or starting material in academic and industrial R&D for exploring new synthetic methodologies.

Basic Information

Product Name	cis-2-Aminomethyl-1-Cyclohexanol Hydrochloride
CAS No.	28250-37-5
Molecular Formula	C7H15NO • HCl
Molecular Weight	165.66 g/mol (Free base: 129.20 g/mol)
Synonyms	(1R,2S)-2-(Aminomethyl)cyclohexanol hydrochloride; cis-2-(Aminomethyl)cyclohexanol HCl; 2-(Aminomethyl)cyclohexanol hydrochloride (cis-); (1S,2R)-2-(Aminomethyl)cyclohexanol hydrochloride; trans-2-Aminomethylcyclohexanol hydrochloride (isomer); 2-(Aminomethyl)-1-cyclohexanol hydrochloride; Aminomethylcyclohexanol HCl; Cyclohexanol, 2-(aminomethyl)-, hydrochloride, cis-
EINECS	Contact for details

Quality Control

Our cis-2-Aminomethyl-1-Cyclohexanol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm isomeric composition, and identity confirmation via IR and NMR spectroscopy. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% cis-isomer
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.