Description

(R)-1-Bromo-4-(Methylsulfinyl)Benzene CAS NO 28227-62-5 is a high-purity chiral building block featuring a bromine substituent and a methylsulfinyl group in a specific stereochemical configuration. This compound is valued for its role as a versatile intermediate in asymmetric synthesis, enabling the construction of complex molecules with defined stereocenters. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for constructing sulfur-containing bioactive molecules.
• Asymmetric Synthesis: Utilized in catalytic cross-coupling reactions and nucleophilic substitutions to introduce the (R)-configured arylsulfinyl moiety into target compounds.
• Agrochemical Research: Serves as a precursor in the synthesis of chiral ligands and potential active ingredients for crop protection products.
• Material Science: Investigated for the development of chiral dopants, liquid crystals, and organic electronic materials due to its specific stereochemistry and functional groups.
• Chemical Biology & Proteomics: Can be used as a reagent for protein labeling or as a building block for activity-based probes targeting cysteine residues.

Basic Information

Product Name	(R)-1-Bromo-4-(Methylsulfinyl)Benzene
CAS No.	28227-62-5
Molecular Formula	C7H7BrOS
Molecular Weight	219.10 g/mol
Synonyms	(R)-4-Bromophenyl Methyl Sulfoxide; (R)-p-Bromophenyl Methyl Sulfoxide; (R)-Methyl 4-Bromophenyl Sulfoxide; (R)-1-Bromo-4-(Methylsulfinyl)benzene; (R)-Bromophenyl Methyl Sulfoxide; (R)-Bromophenylmethylsulfoxide; (R)-4-Bromobenzenesulfinylmethane
EINECS	Contact for details

Quality Control

Our production of (R)-1-Bromo-4-(Methylsulfinyl)Benzene adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, NMR, and GC/MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.