Description

4-(1,1,2,2-Tetrafluoroethoxy)Nitrobenzene is a specialized fluorinated aromatic nitro compound, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring a tetrafluoroethoxy substituent, makes it a valuable intermediate for introducing fluorine-containing motifs into target molecules, which is essential for modifying physical, chemical, and biological properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients, as well as by material scientists exploring specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used to create novel fluorinated pesticides and herbicides, where the fluorine atoms enhance bioavailability and environmental stability.
• Material Science Research: Building block for developing fluorinated liquid crystals, organic semiconductors, and specialty polymers with unique dielectric properties.
• Organic Synthesis Reagent: Serves as a versatile electrophile in nucleophilic aromatic substitution reactions to introduce fluorinated side chains.
• Dye and Pigment Intermediate: Potential use in the synthesis of specialized fluorinated dyes for high-performance applications.

Basic Information

Product Name	4-(1,1,2,2-Tetrafluoroethoxy)Nitrobenzene
CAS No.	28202-32-6
Molecular Formula	C8H5F4NO3
Molecular Weight	239.13 g/mol
Synonyms	1-Nitro-4-(1,1,2,2-tetrafluoroethoxy)benzene; p-(1,1,2,2-Tetrafluoroethoxy)nitrobenzene; 4-Nitrophenyl 1,1,2,2-tetrafluoroethyl ether; Benzene, 1-nitro-4-(1,1,2,2-tetrafluoroethoxy)-; Nitrobenzene, 4-(1,1,2,2-tetrafluoroethoxy)-; 28202-32-6; Tetrafluoroethoxy Nitrobenzene
EINECS	Contact for details

Quality Control

Our 4-(1,1,2,2-Tetrafluoroethoxy)Nitrobenzene is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality systems are designed to support cGMP and ISO standards for reliable and consistent supply to critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider maintaining under an inert atmosphere (e.g., nitrogen or argon) to preserve stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.