Description

3-(4-Hydroxy-3,5-Dimethylphenyl)-2-Methylquinazolin-4(3H)-One is a specialized quinazolinone derivative, a key heterocyclic building block valued for its structural complexity and functional groups. This compound matters for its role as a crucial intermediate in advanced organic synthesis, enabling the development of novel molecules with targeted properties. Industries such as pharmaceutical research, agrochemical development, and advanced material science require this high-purity intermediate for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing kinase inhibitory activity.
• Agrochemical Synthesis: Serves as a precursor for developing novel herbicides, fungicides, or plant growth regulators that leverage the quinazolinone core for bioactivity.
• Organic Light-Emitting Diode (OLED) Materials: Used in the synthesis of electron-transporting or host materials for display and lighting technologies due to its rigid, conjugated structure.
• Ligand for Catalysis: Potential utility in designing specialized ligands for transition metal catalysts used in asymmetric synthesis.
• Academic & Industrial R&D: Employed in chemical libraries for high-throughput screening and structure-activity relationship (SAR) studies in medicinal chemistry.
• Dye & Pigment Intermediate: Acts as a precursor for creating specialized heterocyclic dyes with specific light-absorption properties.

Basic Information

Item	Details
Product Name	3-(4-Hydroxy-3,5-Dimethylphenyl)-2-Methylquinazolin-4(3H)-One
CAS No.	27945-43-3
Molecular Formula	C18H16N2O2
Molecular Weight	292.33 g/mol
Synonyms	2-Methyl-3-(4-hydroxy-3,5-dimethylphenyl)-4(3H)-quinazolinone; 3-(4-Hydroxy-3,5-dimethylphenyl)-2-methyl-4(3H)-quinazolinone; 2-Methyl-3-(4-hydroxy-3,5-dimethylphenyl)quinazolin-4(3H)-one; Quinazolin-4(3H)-one, 3-(4-hydroxy-3,5-dimethylphenyl)-2-methyl-; 27945-43-3; 4(3H)-Quinazolinone, 3-(4-hydroxy-3,5-dimethylphenyl)-2-methyl-
EINECS	Contact for details

Quality Control

Our 3-(4-Hydroxy-3,5-Dimethylphenyl)-2-Methylquinazolin-4(3H)-One is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.