Description

Piperidinophosphonic Acid Dibutyl Ester is a specialized organophosphorus compound with a unique piperidine-phosphonate structure, serving as a valuable intermediate in advanced chemical synthesis. Its primary commercial value lies in its role as a key building block for creating complex molecules, particularly in the development of pharmaceuticals and functional materials. This high-purity intermediate is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate phosphonate or piperidine motifs into their target compounds.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting neurological or metabolic pathways.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, pesticides, and plant growth regulators that utilize phosphonate chemistry.
• Ligand & Catalyst Precursor: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal complexation.
• Material Science Research: Employed in the development of novel polymers, flame retardants, or additives where the piperidine-phosphonate unit imparts specific properties.
• Chemical Biology Probes: Useful in medicinal chemistry for constructing enzyme inhibitors or molecular probes that interact with biological phosphate-binding sites.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, multi-step synthetic routes.

Basic Information

Product Name	Piperidinophosphonic Acid Dibutyl Ester
CAS No.	27933-07-9
Molecular Formula	C13H28NO3P
Molecular Weight	277.34 g/mol
Synonyms	Dibutyl Piperidin-1-ylphosphonate; 1-Piperidinophosphonic Acid Dibutyl Ester; Dibutyl (1-Piperidinyl)phosphonate; Phosphonic Acid, P-(1-Piperidinyl)-, Dibutyl Ester; NSC 163082; Piperidin-1-ylphosphonic Acid Dibutyl Ester; Butyl Piperidin-1-ylphosphonate; P,P-Dibutyl P-(1-Piperidinyl)phosphonate
EINECS	Contact for details

Quality Control

Every batch of Piperidinophosphonic Acid Dibutyl Ester is manufactured and tested under a strict quality management system to ensure consistency and reliability for your synthetic processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (by GC/HPLC), identity (IR, NMR), and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.