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2,4-Dichloro-6,7-Dimethoxyquinazoline CAS NO 27631-29-4


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CAS No.:27631-29-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2,4-Dichloro-6,7-Dimethoxyquinazoline is a high-value, multi-functional heterocyclic building block and key pharmaceutical intermediate. This compound is critical for the synthesis of complex molecules, particularly in the development of kinase inhibitors and other targeted therapeutic agents. It is primarily sought after by research institutions, fine chemical manufacturers, and pharmaceutical companies engaged in drug discovery and process development.

Application

  • Pharmaceutical Intermediate: A crucial precursor in the synthesis of tyrosine kinase inhibitors (TKIs) and other small-molecule drug candidates.
  • Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex quinazoline-based scaffolds due to its reactive chlorine and methoxy substituents.
  • Agrochemical Research: Serves as a starting material for developing novel herbicides and plant growth regulators.
  • Material Science: Investigated for the creation of advanced organic electronic materials and ligands for metal-organic frameworks (MOFs).
  • Biochemical Research: Utilized in the design and synthesis of enzyme inhibitors and molecular probes for biological studies.

Basic Information

Product Name 2,4-Dichloro-6,7-Dimethoxyquinazoline
CAS No. 27631-29-4
Molecular Formula C₁₀H₈Cl₂N₂O₂
Molecular Weight 259.09 g/mol
Synonyms 6,7-Dimethoxy-2,4-dichloroquinazoline; 2,4-Dichloro-6,7-dimethoxyquinazoline; Quinazoline, 2,4-dichloro-6,7-dimethoxy-; 27631-29-4; 2,4-Dichloro-6,7-bis(methoxy)quinazoline; 6,7-Dimethoxy-2,4-dichloro-1,3-diazanaphthalene
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Quality Control

Our 2,4-Dichloro-6,7-Dimethoxyquinazoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements of pharmaceutical R&D and fine chemical synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent high quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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