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2,4-Dichloro-6,7-Dimethoxyquinazoline CAS NO 27631-29-4
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CAS No.:27631-29-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2,4-Dichloro-6,7-Dimethoxyquinazoline is a high-value, multi-functional heterocyclic building block and key pharmaceutical intermediate. This compound is critical for the synthesis of complex molecules, particularly in the development of kinase inhibitors and other targeted therapeutic agents. It is primarily sought after by research institutions, fine chemical manufacturers, and pharmaceutical companies engaged in drug discovery and process development.
Application
- Pharmaceutical Intermediate: A crucial precursor in the synthesis of tyrosine kinase inhibitors (TKIs) and other small-molecule drug candidates.
- Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex quinazoline-based scaffolds due to its reactive chlorine and methoxy substituents.
- Agrochemical Research: Serves as a starting material for developing novel herbicides and plant growth regulators.
- Material Science: Investigated for the creation of advanced organic electronic materials and ligands for metal-organic frameworks (MOFs).
- Biochemical Research: Utilized in the design and synthesis of enzyme inhibitors and molecular probes for biological studies.
Basic Information
| Product Name | 2,4-Dichloro-6,7-Dimethoxyquinazoline |
| CAS No. | 27631-29-4 |
| Molecular Formula | C₁₀H₈Cl₂N₂O₂ |
| Molecular Weight | 259.09 g/mol |
| Synonyms | 6,7-Dimethoxy-2,4-dichloroquinazoline; 2,4-Dichloro-6,7-dimethoxyquinazoline; Quinazoline, 2,4-dichloro-6,7-dimethoxy-; 27631-29-4; 2,4-Dichloro-6,7-bis(methoxy)quinazoline; 6,7-Dimethoxy-2,4-dichloro-1,3-diazanaphthalene |
| EINECS | Contact for details |
Quality Control
Our 2,4-Dichloro-6,7-Dimethoxyquinazoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements of pharmaceutical R&D and fine chemical synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent high quality.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 10 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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