Description

Cyclohexanemethanamine,A-Methyl-, Hydrochloride (1:1) is a high-purity organic amine salt with the CAS number 27586-72-7. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, valued for its defined stereochemistry and structural rigidity. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing active pharmaceutical ingredients (APIs) and specialty compounds.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of complex drug molecules, particularly in central nervous system (CNS) and cardiovascular research.
• Asymmetric Synthesis: Employed as a chiral auxiliary or resolving agent in stereoselective chemical reactions to produce enantiomerically pure compounds.
• Agrochemical Research: Used in the development of novel pesticides and herbicides where the cyclohexylmethylamine scaffold imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a backbone for creating novel ligands used in transition metal catalysis and organocatalysis.
• Fine Chemical Production: Intermediate for manufacturing specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic and R&D Laboratories: Utilized in methodological studies and the discovery of new synthetic pathways in organic chemistry.

Basic Information

Product Name	Cyclohexanemethanamine,A-Methyl-, Hydrochloride (1:1)
CAS No.	27586-72-7
Molecular Formula	C8H17N·HCl
Molecular Weight	163.69 g/mol (Free base: 127.23 g/mol)
Synonyms	(1R,2S)-2-Amino-1-methyl-cyclohexanemethanol hydrochloride; (1R,2S)-rel-2-Amino-1-methylcyclohexanemethanol hydrochloride; (1R,2S)-2-Amino-1-methylcyclohexylmethanol hydrochloride; α-Methylcyclohexanemethylamine hydrochloride; (1R,2S)-2-Amino-1-methyl-1-cyclohexanemethanol hydrochloride; (1R,2S)-2-Amino-1-methylcyclohexanecarbinol hydrochloride; rel-(1R,2S)-2-Amino-1-methylcyclohexanemethanol hydrochloride
EINECS	Contact for details

Quality Control

Our Cyclohexanemethanamine,A-Methyl-, Hydrochloride (1:1) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the exacting standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.