Description

3-Chloro-2H-Benzo[B][1,4]Oxazin-2-One is a versatile heterocyclic organic compound that serves as a critical synthetic intermediate and building block in advanced chemical synthesis. Its unique benzo-fused oxazinone structure with a reactive chloro substituent makes it a valuable precursor for developing novel pharmaceuticals and agrochemicals. This high-purity intermediate is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobial compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the chlorinated oxazinone core contributes to biological activity.
• Organic Synthesis Reagent: Serves as a versatile electrophile and scaffold in organic chemistry for constructing complex heterocyclic systems via nucleophilic substitution and cyclization reactions.
• Material Science Research: Investigated as a monomer or precursor for developing specialty polymers, dyes, and photoactive materials due to its fused aromatic system.
• Chemical Biology Probe Development: Utilized in medicinal chemistry to create molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	3-Chloro-2H-Benzo[B][1,4]Oxazin-2-One
CAS No.	27383-81-9
Molecular Formula	C8H4ClNO2
Molecular Weight	181.58 g/mol
Synonyms	3-Chloro-2H-1,4-benzoxazin-2-one; 3-Chloro-2H-benzo-1,4-oxazin-2-one; 3-Chloro-2H-1,4-benzoxazine-2-one; 3-Chlorobenzo-1,4-oxazin-2-one; 3-Chloro-2H-benzo[b][1,4]oxazin-2-one; 3-Chloro-2H-benzo-1,4-oxazine-2-one; 3-Chloro-2H-1,4-benzoxazin-2(3H)-one (tautomer); 27383-81-9
EINECS	Contact for details

Quality Control

Our 3-Chloro-2H-Benzo[B][1,4]Oxazin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment ensures batch-to-batch consistency and reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging, or stored in darkness.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.