Description

4,4'-Bis-(Dimethoxy Phosphonomethyl) Biphenyl is a specialized organophosphorus compound with a biphenyl backbone, serving as a key intermediate in advanced material synthesis. Its value lies in its dual phosphonate ester functionality, which provides versatile reactivity for constructing complex molecular architectures with tailored properties. This product is essential for R&D and production teams in the pharmaceutical, agrochemical, and specialty polymer industries, where it is used to develop novel active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting bone diseases or requiring phosphonate-based bioisosteres.
• Agrochemical Synthesis: Used in the production of advanced herbicides and plant growth regulators that leverage its phosphonate moiety for enhanced activity and stability.
• Ligand and Catalyst Precursor: Serves as a starting material for creating sophisticated chelating ligands and organometallic catalysts used in asymmetric synthesis and polymerization processes.
• Flame Retardant Synergist: Incorporated into polymer formulations, such as epoxy resins or polycarbonates, to improve flame retardancy and thermal stability.
• Material Science Research: Employed in the development of metal-organic frameworks (MOFs), covalent organic frameworks (COFs), and other functional porous materials.
• Cross-linking Agent: Functions as a reactive monomer or cross-linker in the manufacture of specialty coatings, adhesives, and high-temperature polymers.

Basic Information

Product Name	4,4'-Bis-(Dimethoxy Phosphonomethyl) Biphenyl
CAS No.	27344-43-0
Molecular Formula	C20H28O8P2
Molecular Weight	466.37 g/mol
Synonyms	Biphenyl-4,4'-diylbis(methylene) bis(dimethyl phosphonate); Dimethyl (4,4'-biphenyldiyl)dimethylenediphosphonate; 4,4'-Bis(dimethoxyphosphorylmethyl)biphenyl; Tetramethyl [4,4'-biphenylbis(methylene)]diphosphonate; 4,4'-Bis(methoxymethylphosphonylmethyl)biphenyl; Biphenyl-4,4'-diylbis(methylphosphonic acid) tetramethyl ester; [1,1'-Biphenyl]-4,4'-dimethanol, bis(dimethyl phosphonate)
EINECS	Contact for details

Quality Control

Our 4,4'-Bis-(Dimethoxy Phosphonomethyl) Biphenyl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with relevant standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The product may be hygroscopic; ensure containers are sealed after use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.