Description

(25S)-5α-Spirostane-2α,3β,27-Triol CAS NO 27303-32-8 is a high-purity, steroidal sapogenin derivative characterized by its specific hydroxylation pattern at the 2α, 3β, and 27 positions. This compound serves as a crucial advanced pharmaceutical intermediate and a valuable reference standard for analytical and research purposes. It is primarily needed by pharmaceutical R&D teams, contract research organizations (CROs), and manufacturers of fine chemicals for the synthesis of novel steroid-based therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex steroid-based drugs and bioactive molecules.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control (QC) of related steroid compounds.
• Biochemical Research: Employed in studies investigating steroid biosynthesis pathways, enzyme inhibition, and receptor binding activities.
• Fine Chemical Synthesis: Serves as a precursor for the development of novel chemical entities in medicinal chemistry programs.
• Academic Research: Utilized in universities and research institutes for studies in organic chemistry, pharmacology, and natural product chemistry.

Basic Information

Product Name	(25S)-5α-Spirostane-2α,3β,27-Triol
CAS No.	27303-32-8
Molecular Formula	C27H44O5
Molecular Weight	448.64 g/mol
Synonyms	(25S)-Spirostane-2α,3β,27-triol; 2α,3β,27-Trihydroxy-5α-spirostan; 27-Hydroxydiosgenin; 5α-Spirostane-2α,3β,27-triol, (25S)-; Diosgenin, 27-hydroxy-; (25S)-2α,3β,27-Trihydroxyspirostan-5α-yl
EINECS	Contact for details

Quality Control

Our (25S)-5α-Spirostane-2α,3β,27-Triol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.