Description

4-Fluoro-4-Deoxy-β-D-Glucopyranose is a fluorinated monosaccharide derivative, serving as a critical building block in synthetic carbohydrate chemistry. Its value lies in its role as a stable, non-hydrolyzable mimic of glucose, enabling the study and modulation of biological processes involving sugar metabolism and recognition. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for developing enzyme inhibitors, glycomimetic drugs, and molecular probes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel glycomimetic drugs and enzyme inhibitors targeting metabolic disorders.
• Biochemical Research: Used as a stable, fluorinated analog of D-glucose to study carbohydrate-processing enzymes, transporters, and receptor interactions.
• Glycobiology Probe Development: Acts as a building block for creating labeled or tagged carbohydrate probes for diagnostic and imaging applications.
• Enzyme Mechanism Studies: Employed to investigate the catalytic mechanisms of glycosidases and glycosyltransferases due to the fluorine atom's electronic and steric properties.
• Antiviral & Antibacterial Agent Research: Serves as a scaffold for developing nucleoside analogs and other antimicrobial compounds that interfere with microbial sugar metabolism.
• Chemical Biology Tool: Utilized in activity-based protein profiling (ABPP) and other chemoproteomic approaches to identify and characterize carbohydrate-active enzymes.

Basic Information

Product Name	4-Fluoro-4-Deoxy-β-D-Glucopyranose
CAS No.	27108-04-9
Molecular Formula	C6H11FO5
Molecular Weight	182.15 g/mol
Synonyms	4-Deoxy-4-fluoro-D-glucopyranose; 4-Fluoro-4-deoxy-D-glucose; 4-FDG; 4-Fluoro-D-glucose; 4-Fluoro-β-D-glucopyranose; β-4-Fluoro-4-deoxyglucose; (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-fluorooxane-2,3,4-triol
EINECS	Contact for details

Quality Control

Our 4-Fluoro-4-Deoxy-β-D-Glucopyranose is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and pharmaceutical development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.