Description

(1S-Trans)-2,2-Dimethyl-3-(2-Methylprop-1-Enyl)Cyclopropanecarbonyl Chloride is a high-purity, optically active cyclopropane derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in its role as a reactive acyl chloride intermediate, enabling the efficient introduction of the chrysanthemic acid moiety into target molecules. This compound is essential for manufacturers in the agrochemical and pharmaceutical industries who require precise stereochemistry for developing active ingredients and fine chemicals.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of pyrethroid and pyrethrin insecticides, where the (1S-trans) stereochemistry is crucial for high biological activity.
• Pharmaceutical Synthesis: Used as a chiral synthon for constructing complex molecules in medicinal chemistry and active pharmaceutical ingredient (API) development.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require the chrysanthemate structure.
• Research & Development: Serves as a standard and starting material in academic and industrial R&D for studying cyclopropane chemistry and asymmetric synthesis.
• Chemical Derivatization: The reactive acid chloride group facilitates amide and ester formation, allowing for the creation of diverse chemical libraries.

Basic Information

Product Name	(1S-Trans)-2,2-Dimethyl-3-(2-Methylprop-1-Enyl)Cyclopropanecarbonyl Chloride
CAS No.	26770-95-6
Molecular Formula	C10H15ClO
Molecular Weight	186.68 g/mol
Synonyms	(+)-trans-Chrysanthemoyl chloride; (1R,3R)-2,2-Dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropane-1-carbonyl chloride; (1R-trans)-2,2-Dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarbonyl chloride; d-trans-Chrysanthemic acid chloride; (1R,3R)-Chrysanthemoyl chloride; (+)-trans-Chrysanthemic acid chloride; (1R,3R)-2,2-Dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarbonyl chloride
EINECS	Contact for details

Quality Control

Our (1S-Trans)-2,2-Dimethyl-3-(2-Methylprop-1-Enyl)Cyclopropanecarbonyl Chloride is produced under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral purity analysis by HPLC and GC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee (1S-trans)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.