Description

4-(Hydroxymethyl)-1-Azabicyclo[2.2.2]Octane is a versatile bicyclic tertiary amine derivative, valued for its unique bridged quinuclidine-like structure and functional hydroxymethyl group. This compound serves as a critical advanced pharmaceutical intermediate and a sophisticated building block in organic synthesis. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting the nervous system, due to its structural similarity to bioactive alkaloids.
• Ligand & Catalyst Synthesis: Used to construct sophisticated nitrogen-containing ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Employed as a building block for developing new crop protection agents and plant growth regulators.
• Polymer Modification: Acts as a functional monomer or cross-linking agent to introduce amine functionality and rigidity into polymer chains.
• Chemical Biology Probes: Utilized in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Academic & Industrial R&D: Serves as a valuable scaffold for medicinal chemistry and novel material discovery in research laboratories.

Basic Information

Product Name	4-(Hydroxymethyl)-1-Azabicyclo[2.2.2]Octane
CAS No.	26608-58-2
Molecular Formula	C8H15NO
Molecular Weight	141.21 g/mol
Synonyms	1-Azabicyclo[2.2.2]octan-4-ylmethanol; 4-(Hydroxymethyl)quinuclidine; Quinuclidin-4-ylmethanol; 4-Hydroxymethylquinuclidine; 4-Quinuclidinemethanol; 4-(Hydroxymethyl)-1-azabicyclo[2.2.2]octane; 1-Azabicyclo[2.2.2]octane-4-methanol
EINECS	Contact for details

Quality Control

Our 4-(Hydroxymethyl)-1-Azabicyclo[2.2.2]Octane is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere for long-term storage to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.