Description

p-(1-Aziridinyl)-n-[(5-Methoxy-2-Pyrimidinyl)Carbamoyl]Phosphonamidic Acid Ethyl Ester is a specialized organophosphorus compound featuring a unique aziridine and pyrimidine pharmacophore. This structure makes it a valuable high-purity chemical intermediate for advanced research and synthesis. It is primarily utilized by pharmaceutical R&D and agrochemical discovery teams in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of experimental drug candidates, particularly those targeting enzyme inhibition.
• Agrochemical Research: Serves as a precursor for novel herbicides, insecticides, or plant growth regulators under investigation.
• Chemical Biology Probe: Used in academic and industrial research to study biological pathways involving phosphorylation or nucleophilic attack.
• Custom Synthesis: Employed by fine chemical manufacturers for the contract production of complex, target-specific molecules.
• Material Science Research: Potential monomer or cross-linking agent in the development of specialty polymers with tailored properties.

Basic Information

Product Name	p-(1-Aziridinyl)-n-[(5-Methoxy-2-Pyrimidinyl)Carbamoyl]Phosphonamidic Acid Ethyl Ester
CAS No.	26594-10-5
Molecular Formula	C₁₂H₁₈N₅O₅P
Molecular Weight	343.28 g/mol
Synonyms	Ethyl p-(1-aziridinyl)-N-[(5-methoxy-2-pyrimidinyl)carbamoyl]phosphonamidate; Phosphonamidic acid, P-(1-aziridinyl)-N-[(5-methoxy-2-pyrimidinyl)carbamoyl]-, ethyl ester; Aziridine phosphonamidate derivative; 5-Methoxy-2-pyrimidinyl carbamoyl phosphonamidate; NSC 163049
EINECS	Contact for details

Quality Control

Every batch of p-(1-Aziridinyl)-n-[(5-Methoxy-2-Pyrimidinyl)Carbamoyl]Phosphonamidic Acid Ethyl Ester is manufactured and tested under a strict quality management system. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles to ensure it meets your precise research or synthesis requirements. Our quality commitment supports compliance with cGMP and ISO 9001 standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.