Description

3-[3-(Trifluoromethyl)Phenyl]Sydnone is a specialized heterocyclic organic compound featuring a sydnone core substituted with a 3-(trifluoromethyl)phenyl group. This structure is of significant interest in advanced organic synthesis and pharmaceutical research, particularly as a versatile intermediate for constructing complex molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate unique nitrogen-oxygen heterocycles and trifluoromethyl motifs into their target compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or inflammatory diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the biological activity of the sydnone ring and the lipophilicity of the CF3 group.
• Material Science Precursor: Serves as a monomer or functional additive in the research of advanced polymers and functional materials with specific electronic or thermal properties.
• Chemical Biology Probe: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a probe molecule in biochemical assays.
• Organic Synthesis Reagent: Acts as a dipolarophile or a unique reactant in cycloaddition reactions and other transformations to create complex heterocyclic scaffolds.

Basic Information

Product Name	3-[3-(Trifluoromethyl)Phenyl]Sydnone
CAS No.	26537-62-2
Molecular Formula	C9H5F3N2O2
Molecular Weight	230.14 g/mol
Synonyms	3-[3-(Trifluoromethyl)phenyl]-1,2,3-oxadiazol-3-ium-5-olate; 3-(3-Trifluoromethylphenyl)sydnone; 3-(α,α,α-Trifluoro-m-tolyl)sydnone; m-(Trifluoromethyl)phenylsydnone; 3-(3-(Trifluoromethyl)phenyl)-1,2,3-oxadiazolium-5-olate
EINECS	Contact for details

Quality Control

Our 3-[3-(Trifluoromethyl)Phenyl]Sydnone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.