Description

1-(1-Adamantyl)-2-Bromopropan-1-One is a specialized brominated adamantane derivative, serving as a high-value synthetic intermediate. This compound is prized for its unique adamantyl cage structure, which imparts significant steric bulk and stability, making it a critical building block in advanced organic synthesis. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and viral infections.
• Agrochemical Research: Used in developing new generation pesticides and herbicides, where the adamantyl group can enhance biological activity and environmental stability.
• Material Science: Serves as a monomer or cross-linking agent in the development of advanced polymers with high thermal and chemical resistance.
• Organic Synthesis Building Block: Employed in C-C bond formation reactions, such as Suzuki-Miyaura cross-coupling, to introduce the functionalized adamantyl moiety into complex molecules.
• Ligand and Catalyst Development: Utilized for creating novel phosphine or N-heterocyclic carbene (NHC) ligands for asymmetric catalysis.

Basic Information

Product Name	1-(1-Adamantyl)-2-Bromopropan-1-One
CAS No.	26525-24-6
Molecular Formula	C13H19BrO
Molecular Weight	271.20 g/mol
Synonyms	2-Bromo-1-(1-adamantyl)-1-propanone; 1-Adamantyl 2-bromopropyl ketone; 2-Bromo-1-tricyclo[3.3.1.13,7]dec-1-ylpropan-1-one; 1-(Tricyclo[3.3.1.13,7]dec-1-yl)-2-bromopropan-1-one; Adamantan-1-yl 2-bromopropyl ketone; Bromo Adamantyl Propanone
EINECS	Contact for details

Quality Control

Our 1-(1-Adamantyl)-2-Bromopropan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with all shipments, detailing batch-specific results. Our quality commitment ensures the material meets the stringent requirements for research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.