Description

Humulone is a key alpha acid compound primarily derived from the hop plant (*Humulus lupulus*). This compound is highly valued for its role as a precursor to iso-alpha acids, which are essential for imparting the characteristic bitter flavor and aroma in beer brewing. It is also of significant interest in the pharmaceutical and nutraceutical industries due to its researched bioactive properties. Industries requiring high-purity botanical extracts or specialized flavoring agents will find this product essential for their formulations.

Application

• Primary bittering agent and flavor precursor in the commercial beer brewing industry.
• Raw material for the production of iso-alpha acids and reduced iso-alpha acids (e.g., tetrahydroiso-alpha acids) used in brewing.
• Active pharmaceutical ingredient (API) intermediate in nutraceutical and dietary supplement formulations targeting anti-inflammatory or calming effects.
• Reference standard for analytical testing and quality control in food, beverage, and botanical extract laboratories.
• Starting material for research into its potential antimicrobial, antioxidant, and cancer chemopreventive properties.
• Component in specialized natural flavoring systems and food additives.

Basic Information

Product Name	Humulone
CAS No.	26472-41-3
Molecular Formula	C21H30O5
Molecular Weight	362.46 g/mol
Synonyms	α-Lupulic acid; α-Humulone; (3R,4S,5R,6S)-3,4,5-Trihydroxy-4,6-bis(3-methylbut-2-en-1-yl)-2-(2-methylpropanoyl)cyclohexa-2,5-dien-1-one; 1,3,4,5-Tetrahydroxy-6,6-bis(3-methyl-2-butenyl)-4-(3-methyl-1-oxobutyl)-2,4-cyclohexadien-1-one; Hop alpha acid; Humulon; Common Hop Resin
EINECS	Contact for details

Quality Control

Our Humulone is produced and tested under a strict quality management system to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) for each lot, detailing parameters such as assay, related substances, and residual solvents. The product meets specifications suitable for food-grade and research applications. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to pale brown powder or resin
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥95.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals (as Pb)	≤20 ppm
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.