Description

2-Amino-2-(1,2,3,4-Tetrahydronaphthalen-1-Yl)Acetic Acid is a specialized chiral amino acid derivative featuring a tetralin (1,2,3,4-tetrahydronaphthalene) moiety. This compound is a critical pharmaceutical intermediate and a versatile building block in organic synthesis, valued for its unique structural framework that enables the construction of complex molecules. It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of new active ingredients and chiral ligands.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of novel drug candidates, particularly for central nervous system (CNS) targets.
• Asymmetric Synthesis: Serves as a precursor for chiral auxiliaries, catalysts, and ligands used in enantioselective chemical transformations.
• Peptidomimetics Research: Used to incorporate constrained, non-natural amino acid structures into peptide analogs to enhance stability and biological activity.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.
• Agrochemical Development: Potential intermediate in the synthesis of advanced, high-specificity crop protection agents.
• Academic & Industrial R&D: Fundamental building block for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	2-Amino-2-(1,2,3,4-Tetrahydronaphthalen-1-Yl)Acetic Acid
CAS No.	26368-32-1
Molecular Formula	C₁₂H₁₅NO₂
Molecular Weight	205.25 g/mol
Synonyms	1-Tetralinylglycine; 2-Amino-2-(1,2,3,4-tetrahydro-1-naphthyl)acetic acid; (1,2,3,4-Tetrahydro-1-naphthyl)glycine; α-Amino-1,2,3,4-tetrahydro-1-naphthaleneacetic acid; 2-Amino-2-(1,2,3,4-tetrahydro-naphthalen-1-yl)-acetic acid; 1,2,3,4-Tetrahydro-1-naphthylglycine; (1-Tetralinyl)glycine; NSC 163023
EINECS	Contact for details

Quality Control

Our production of 2-Amino-2-(1,2,3,4-Tetrahydronaphthalen-1-Yl)Acetic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the exacting standards required for pharmaceutical R&D and advanced synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.