Description

trans-2-Hydrazinocyclopentanol CAS NO 26280-49-9 is a versatile chiral hydrazine derivative featuring a cyclopentane backbone. This compound is valued for its bifunctional reactivity, serving as a key chiral building block and ligand precursor in sophisticated organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of active pharmaceutical ingredients (APIs), chiral catalysts, and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the asymmetric synthesis of novel drug candidates, particularly in developing central nervous system (CNS) agents and enzyme inhibitors.
• Catalyst & Ligand Precursor: Used to synthesize novel chiral ligands for asymmetric catalysis, enabling high enantioselectivity in hydrogenation and other key transformations.
• Agrochemical Research: Employed in the development of advanced, chiral active ingredients for herbicides and pesticides with improved efficacy and environmental profiles.
• Fine Chemical Synthesis: Serves as a versatile building block for constructing complex nitrogen-containing heterocycles and other specialty fine chemicals.
• Academic & Industrial R&D: Essential for methodological research in organic chemistry, exploring new synthetic routes and reaction mechanisms.

Basic Information

Product Name	trans-2-Hydrazinocyclopentanol
CAS No.	26280-49-9
Molecular Formula	C5H12N2O
Molecular Weight	116.16 g/mol
Synonyms	(1R,2R)-2-Hydrazinylcyclopentan-1-ol; (1R,2R)-2-Hydrazinocyclopentanol; trans-2-Hydrazinocyclopentanol; (1R,2R)-1,2-Cyclopentanediol, 2-hydrazinyl-; 2-Hydrazinocyclopentanol; Cyclopentanol, 2-hydrazino-, trans-; (R,R)-2-Hydrazinocyclopentanol
EINECS	Contact for details

Quality Control

Our trans-2-Hydrazinocyclopentanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and process development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C to minimize oxidation and moisture absorption. Allow the container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (trans isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.