Description

4-Hydroxy-2-Adamantone is a versatile and highly functionalized adamantane derivative, serving as a critical advanced intermediate in organic synthesis. Its unique bridged polycyclic structure with a ketone and hydroxyl group offers precise stereochemical control and reactivity for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing novel active pharmaceutical ingredients (APIs) and high-performance materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of antiviral agents, neuraminidase inhibitors, and other bioactive molecules.
• Organic Synthesis: Serves as a rigid scaffold and chiral precursor in asymmetric synthesis and catalyst design.
• Material Science: Used in the development of advanced polymers, dendrimers, and liquid crystalline materials with enhanced thermal stability.
• Agrochemical Research: Intermediate for creating novel fungicides and herbicides with specific mode-of-action profiles.
• Chemical Biology: Probe molecule for studying enzyme interactions and protein binding sites due to its defined three-dimensional structure.
• Cosmetic Ingredient Synthesis: Precursor for UV-absorbing compounds and stabilizers in high-end cosmetic formulations.

Basic Information

Product Name	4-Hydroxy-2-Adamantone
CAS No.	26278-43-3
Molecular Formula	C10H14O2
Molecular Weight	166.22 g/mol
Synonyms	2-Adamantanone, 4-hydroxy-; 4-Hydroxyadamantan-2-one; 4-Hydroxy-2-adamantanone; 2-Oxo-4-hydroxyadamantane; 4-Hydroxytricyclo[3.3.1.13,7]decan-2-one; NSC 169854
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-2-Adamantone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.