Description

5-Oxo-2'-Phenyl-L-Prolinohydrazide is a high-purity, non-proteinogenic amino acid derivative with a proline-based structure. This compound is valued for its role as a key chiral building block and intermediate in advanced organic synthesis, particularly for pharmaceuticals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Peptidomimetics Research: Used in the design and construction of peptidomimetics and constrained peptides to improve metabolic stability and bioavailability.
• Agrochemical Synthesis: Acts as a chiral synthon in the production of advanced, enantiomerically pure pesticides and herbicides.
• Catalyst & Ligand Development: Employed in the development of specialized catalysts and ligands for asymmetric synthesis.
• Bioconjugation & Probe Synthesis: Useful in creating chemical probes and bioconjugates for biochemical and diagnostic applications.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	5-Oxo-2'-Phenyl-L-Prolinohydrazide
CAS No.	26275-69-4
Molecular Formula	C₁₁H₁₃N₃O₂
Molecular Weight	219.24 g/mol
Synonyms	L-Prolinamide, 5-oxo-2-phenyl-; 2-Phenyl-5-oxo-L-prolinohydrazide; (S)-5-Oxo-2-phenylpyrrolidine-2-carbohydrazide; 5-Oxo-2-phenyl-L-proline hydrazide; 2-Phenyl-5-oxoproline hydrazide; 26275-69-4; 5-Oxo-2-phenylprolinohydrazide
EINECS	Contact for details

Quality Control

Our 5-Oxo-2'-Phenyl-L-Prolinohydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.