Description

1,3,4,6-Tetra-o-Acetyl-2-Amino-2-Desoxy-β-D-Glucopyranose Hydrochloride is a key acetylated glycosyl donor and a vital protected intermediate in carbohydrate chemistry. Its primary value lies in enabling the efficient and selective synthesis of complex oligosaccharides and glycoconjugates, which are fundamental to pharmaceutical and biochemical research. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical industry, particularly for the development of novel glycosidase inhibitors, antiviral agents, and other bioactive carbohydrate-based molecules.

Application

• Glycosylation Reactions: A crucial donor molecule for the stereoselective synthesis of β-glycosidic linkages in oligosaccharides.
• Pharmaceutical Intermediates: Serves as a protected precursor in the synthesis of glycosidase inhibitors and other therapeutic agents targeting carbohydrate-processing enzymes.
• Glycoconjugate Synthesis: Used in the preparation of glycopeptides, glycolipids, and other biologically active glycoconjugates for drug discovery and development.
• Biochemical Research: A fundamental tool for studying carbohydrate-protein interactions, enzyme mechanisms, and metabolic pathways.
• Antiviral Drug Development: Acts as a key intermediate in the synthesis of nucleoside analogs and other carbohydrate-based antiviral compounds.
• Custom Synthesis: Employed by fine chemical and CRO/CMO companies for the custom manufacturing of complex, high-value carbohydrate molecules.

Basic Information

Item	Details
Product Name	1,3,4,6-Tetra-o-Acetyl-2-Amino-2-Desoxy-β-D-Glucopyranose Hydrochloride
CAS No.	26108-75-8
Molecular Formula	C14H21ClN2O9
Molecular Weight	396.78 g/mol
Synonyms	2-Acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-β-D-glucopyranose Hydrochloride; N-Acetylglucosamine Tetraacetate Hydrochloride; GlcNAc(Ac)4-HCl; 2-Acetamido-2-deoxy-1,3,4,6-tetra-O-acetyl-β-D-glucopyranose Hydrochloride; β-D-Glucopyranose, 2-(acetylamino)-1,3,4,6-tetrakis-O-acetyl-2-deoxy-, hydrochloride; 1,3,4,6-Tetra-O-acetyl-2-acetamido-2-deoxy-β-D-glucopyranose Hydrochloride; NAG-4Ac-HCl
EINECS	Contact for details

Quality Control

Our 1,3,4,6-Tetra-o-Acetyl-2-Amino-2-Desoxy-β-D-Glucopyranose Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and specific tests for residual solvents and moisture. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with our stringent specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Specific Rotation [α]20/D	+40° to +50° (c=1 in CHCl3)
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.