Description

3,5-Bis(Trifluoromethyl)Benzhydrazide is a high-value, fluorinated aromatic hydrazide derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in the unique reactivity of the hydrazide group combined with the electron-withdrawing properties of the trifluoromethyl substituents, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors who require sophisticated building blocks for drug discovery, crop protection agents, and high-performance polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of compounds targeting central nervous system (CNS) and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl groups enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic frameworks (MOFs/COFs) for applications requiring specific thermal or chemical resistance.
• Chemical Research & Development: A versatile reagent for constructing heterocyclic compounds, such as pyrazoles and indazoles, via cyclization and condensation reactions.

Basic Information

Product Name	3,5-Bis(Trifluoromethyl)Benzhydrazide
CAS No.	26107-82-4
Molecular Formula	C9H6F6N2O
Molecular Weight	272.15 g/mol
Synonyms	[3,5-Bis(trifluoromethyl)phenyl]hydrazide; 3,5-Bis(trifluoromethyl)benzoic acid hydrazide; 3,5-Di(trifluoromethyl)benzhydrazide; α,α,α,α',α',α'-Hexafluoro-3,5-xylene-α,α-dihydrazide; 3,5-Bis(trifluoromethyl)benzohydrazide; Benzhydrazide, 3,5-bis(trifluoromethyl)-; 26107-82-4; 3,5-BTFMBH (abbreviation)
EINECS	Contact for details

Quality Control

Our 3,5-Bis(Trifluoromethyl)Benzhydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our commitment to quality supports compliance with cGMP and ISO 9001 standards for research and industrial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is sensitive to strong alkalis and fluorides; keep away from incompatible materials. For long-term storage, consider using an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.