Description

1-Azabicyclo<2.2.1>Heptane Hydrochloride is a bicyclic amine hydrochloride salt, a versatile and high-purity organic building block. This compound is valued for its rigid, three-dimensional structure, which is crucial for modulating the physicochemical and biological properties of target molecules in advanced research. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs), agrochemicals, and complex specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex drug candidates, particularly those targeting neurological and cardiovascular diseases.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides where its bicyclic scaffold can impart unique activity.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Employed as a molecular scaffold or a tagging reagent in probe development for studying enzyme function and protein-protein interactions.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis, including ring-opening and functionalization reactions.

Basic Information

Product Name	1-Azabicyclo<2.2.1>Heptane Hydrochloride
CAS No.	25979-85-5
Molecular Formula	C6H12ClN
Molecular Weight	133.62 g/mol
Synonyms	1-Azabicyclo[2.2.1]heptane Hydrochloride; 1-Azabicyclo(2.2.1)heptane HCl; 1-Azanorbornane Hydrochloride; Norbornane, 1-aza-, hydrochloride; Endo-2,5-Methano-1-azabicyclo[2.2.1]heptane Hydrochloride; 2,5-Methano-1-azabicyclo[2.2.1]heptane Hydrochloride; Bicyclo[2.2.1]heptane, 1-aza-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 1-Azabicyclo<2.2.1>Heptane Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring GMP-grade starting materials and aligns with ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.