Description

3-(4-Oxoquinazolin-3(4H)-Yl)Propanoic Acid is a high-purity, functionalized quinazolinone derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel pharmacologically active molecules, particularly in medicinal chemistry research. It is primarily needed by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers focused on creating new heterocyclic compounds with targeted biological activities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors, anticancer agents, and other therapeutic candidates targeting various disease pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Used in the research and synthesis of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probes: Functional handle for creating tool compounds and probes to study enzyme function and biological mechanisms.
• Academic & Institutional Research: Employed in universities and research institutes for exploring new heterocyclic chemistry and reaction methodologies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific advanced intermediates under cGMP or research-grade conditions.

Basic Information

Product Name	3-(4-Oxoquinazolin-3(4H)-Yl)Propanoic Acid
CAS No.	25818-88-6
Molecular Formula	C₁₁H₁₀N₂O₃
Molecular Weight	218.21 g/mol
Synonyms	3-(3,4-Dihydro-4-oxoquinazolin-3-yl)propanoic acid; 3-(4-Oxo-3,4-dihydroquinazolin-3-yl)propanoic acid; 3-(4-Oxo-1,4-dihydroquinazolin-3-yl)propanoic acid; Quinazolinone propanoic acid derivative; 25818-88-6; 3-(4-Oxo-3H-quinazolin-3-yl)propanoic acid
EINECS	Contact for details

Quality Control

Our 3-(4-Oxoquinazolin-3(4H)-Yl)Propanoic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment ensures the material meets the high standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.