Description

Polysucrose is a high-molecular-weight, synthetic polymer derived from sucrose, widely recognized for its utility as a density gradient medium in biological separations. Its consistent and inert properties make it an essential tool for achieving high-purity isolations of cells, organelles, and viruses in research and diagnostic applications. This product is critical for laboratories and biopharmaceutical manufacturers requiring reliable, non-ionic media for centrifugation protocols.

Application

• Density Gradient Centrifugation: Primary application for the isolation of lymphocytes, platelets, and other blood cells.
• Virus Purification: Used in the purification and concentration of viruses for vaccine development and virology research.
• Subcellular Fractionation: Effective for separating organelles like mitochondria, nuclei, and peroxisomes from tissue homogenates.
• Molecular Biology: Serves as a medium for the purification of plasmids, cosmids, and other nucleic acids.
• Clinical Diagnostics: Employed in diagnostic test kits for cell-based assays and separation procedures.
• Biopharmaceutical Manufacturing: Aids in downstream processing for the purification of therapeutic proteins and vaccines.

Basic Information

Product Name	Polysucrose
CAS No.	25702-74-3
Molecular Formula	(C12H20O10)n
Molecular Weight	High polymer (Typically 400,000 - 600,000 Da)
Synonyms	Ficoll; Polyfructosan S; Sucrose polymer; Ficoll PM 400; Ficoll 400; Polysucrose 400; Poly(1,2-anhydrofructose)
EINECS	Contact for details

Quality Control

Our Polysucrose is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for research and in-vitro diagnostic use. A comprehensive Certificate of Analysis (COA) detailing purity, molecular weight distribution, and biological performance is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent moisture absorption, which can affect solution density and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0% (as Polysucrose)
Molecular Weight (Avg.)	400,000 ± 50,000 Da
pH (20% w/v solution)	5.0 - 7.5
Loss on Drying	≤ 5.0 %
Residue on Ignition	≤ 0.1 %
Biological Performance	Meets density gradient separation criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.