Description

Trimethylsulfoxonium Bromide is a versatile organosulfur compound widely used as a key reagent in organic synthesis. Its primary value lies in its role as a stable, crystalline ylide source for the Corey-Chaykovsky reaction, enabling the efficient synthesis of epoxides, cyclopropanes, and other strained ring systems. This high-purity intermediate is essential for research and development laboratories, as well as production facilities in the pharmaceutical, agrochemical, and advanced materials sectors seeking reliable and scalable building blocks.

Application

• Pharmaceutical Intermediate: A critical reagent for the synthesis of epoxides and aziridines, which are key structural motifs in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides that incorporate cyclopropane or epoxide functional groups.
• Organic Synthesis Reagent: Employed in the Corey-Chaykovsky reaction for the methylenation of carbonyl compounds to form epoxides and for cyclopropanation reactions.
• Material Science Research: Serves as a precursor or methylene transfer agent in the development of novel polymers and specialty chemicals.
• Academic & R&D: A staple reagent in university and industrial research laboratories for method development and exploring new synthetic pathways.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex molecules for flavors, fragrances, and electronic chemicals.

Basic Information

Product Name	Trimethylsulfoxonium Bromide
CAS No.	25596-24-1
Molecular Formula	C₃H₉BrOS
Molecular Weight	173.07 g/mol
Synonyms	Trimethylsulfoxonium bromide; Sulfoxonium, trimethyl-, bromide (1:1); Trimethyloxosulfonium bromide; (CH3)3SOBr; Trimethylsulfonium oxide bromide; TMSOBr; Methylsulfoxonium methylide precursor; EINECS 247-117-6
EINECS	247-117-6

Quality Control

Our Trimethylsulfoxonium Bromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, KF titration for water content, and residue on ignition analysis, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Melting Point	148 - 152 °C
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.