Description

4-Benzoylpiperidine Hydrochloride is a high-purity organic salt widely utilized as a critical pharmaceutical intermediate and versatile building block in organic synthesis. Its value lies in the piperidine scaffold, a privileged structure in medicinal chemistry, which is functionalized with a benzoyl group to enable the development of novel bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of central nervous system (CNS) active compounds, including potential analgesics, antipsychotics, and neurokinin receptor antagonists.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities targeting various biological pathways.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and pesticides.
• Fine Chemical Production: Employed in custom synthesis and the manufacture of specialty chemicals requiring the 4-benzoylpiperidine moiety.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic synthesis and catalysis studies.

Basic Information

Product Name	4-Benzoylpiperidine Hydrochloride
CAS No.	25519-80-6
Molecular Formula	C₁₂H₁₅NO·HCl
Molecular Weight	225.71 g/mol
Synonyms	1-Benzoylpiperidine hydrochloride; 4-Benzoylpiperidine HCl; Piperidine, 1-benzoyl-, hydrochloride; N-Benzoylpiperidine hydrochloride; 1-Piperidinecarboxylic acid, phenyl-, hydrochloride; α-Phenyl-1-piperidinecarboxylic acid hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Benzoylpiperidine Hydrochloride is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and commercial applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.