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(12R,13R,14R)-12,13-Bis(Acetoxy)-14,19-Dihydro-20-Norcrotalanan-11,15-Dione CAS NO 25490-68-0


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CAS No.:25490-68-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(12R,13R,14R)-12,13-Bis(Acetoxy)-14,19-Dihydro-20-Norcrotalanan-11,15-Dione is a complex, stereochemically defined alkaloid derivative with significant potential as a key synthetic intermediate. Its precise molecular architecture makes it a valuable building block for the development of novel pharmaceutical compounds and advanced research chemicals. This compound is primarily sought by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in synthetic chemistry and drug discovery programs.

Application

  • Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex alkaloids and potential therapeutic agents.
  • Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and the development of new chemical entities.
  • Reference Standard: Employed as a high-purity analytical standard for method development and quality control in research settings.
  • Organic Synthesis: Utilized in advanced synthetic methodologies, including stereoselective transformations, due to its multiple functional groups.
  • Biochemical Research: Investigated for its biological activity and interactions in specialized pharmacological studies.

Basic Information

Item Details
Product Name (12R,13R,14R)-12,13-Bis(Acetoxy)-14,19-Dihydro-20-Norcrotalanan-11,15-Dione
CAS No. 25490-68-0
Molecular Formula C21H25NO7
Molecular Weight 403.43 g/mol
Synonyms 12,13-Diacetoxy-14,19-dihydro-20-norcrotalanan-11,15-dione; Norcrotalanan derivative; (12R,13R)-12,13-Diacetoxy-14,19-dihydro-20-norcrotalanan-11,15-dione; Crotalanan alkaloid intermediate; 25490-68-0; 12,13-Bis(acetyloxy)-14,19-dihydro-20-norcrotalanan-11,15-dione
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Quality Control

Our (12R,13R,14R)-12,13-Bis(Acetoxy)-14,19-Dihydro-20-Norcrotalanan-11,15-Dione is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and spectroscopic identification (NMR, IR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which may affect stability and handling properties.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 97.0%
Chiral Purity ≥ 98.0% de (for specified stereoisomer)
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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