Description

1'H-Spiro[Cyclohexane-1,2'-Quinoline] is a specialized spirocyclic organic compound featuring a unique fused ring structure that combines cyclohexane and quinoline moieties. This molecular architecture makes it a valuable intermediate and building block in advanced organic synthesis, particularly for creating complex heterocyclic frameworks. It is primarily sought after by research institutions and chemical manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or possessing spirocyclic pharmacophores.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Acts as a building block for organic semiconductors, ligands for catalysts, or specialty polymers requiring rigid, three-dimensional structures.
• Dye & Pigment Synthesis: Employed in the creation of advanced colorants and fluorescent markers due to the quinoline component's chromophoric properties.
• Academic & R&D: A valuable compound for methodological studies in organic chemistry, including novel cyclization and functionalization reactions.

Basic Information

Product Name	1'H-Spiro[Cyclohexane-1,2'-Quinoline]
CAS No.	25337-81-9
Molecular Formula	C₁₄H₁₇N
Molecular Weight	199.29 g/mol
Synonyms	Spiro[cyclohexane-1,2'-quinoline]; 1'H-Spiro(cyclohexane-1,2'-quinoline); 1'H-Spiro(cyclohexane-1,2'(1'H)-quinoline); 2,3,4,9-Tetrahydro-1H-1-benzazepine; 1'H-Spiro[cyclohexane-1,2'-quinoline]; 1,2,3,4-Tetrahydrospiro[quinoline-2,1'-cyclohexane]; Spiro[quinoline-2(1H),1'-cyclohexane]
EINECS	Contact for details

Quality Control

Our production of 1'H-Spiro[Cyclohexane-1,2'-Quinoline] adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques, including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage under an inert atmosphere (e.g., nitrogen or argon), please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.