Description

1-Chloro-5-Iodo-2,6-Dimethoxynaphthalene is a halogenated, methoxy-substituted naphthalene derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and highly functionalized chemical building block, offering multiple reactive sites for constructing complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides with enhanced efficacy.
• Liquid Crystal & OLED Material Research: Serves as a core structural unit for developing organic semiconductors and advanced display materials due to its rigid, planar naphthalene core.
• Dye & Pigment Chemistry: Functions as an intermediate for synthesizing specialized dyes and pigments with specific light-absorption properties.
• Cross-Coupling Reactions: The iodine and chlorine substituents make it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create complex biaryl structures.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in organic synthesis and catalysis.

Basic Information

Product Name	1-Chloro-5-Iodo-2,6-Dimethoxynaphthalene
CAS No.	25315-07-5
Molecular Formula	C₁₂H₁₀ClIO₂
Molecular Weight	348.56 g/mol
Synonyms	1-Chloro-5-iodo-2,6-dimethoxynaphthalene; 2,6-Dimethoxy-1-chloro-5-iodonaphthalene; 1-Chloro-5-iodo-2,6-bis(methoxy)naphthalene; NSC 403119; 1-Chloro-5-iodanyl-2,6-dimethoxy-naphthalene
EINECS	Contact for details

Quality Control

Our 1-Chloro-5-Iodo-2,6-Dimethoxynaphthalene is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP principles and adherence to ISO 9001 standards underpin our reliable supply chain for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.