Description

5-Iodo-1,2,3-Trimethoxybenzene is a versatile halogenated aromatic building block characterized by its iodine substituent and three methoxy groups, offering unique reactivity for advanced synthesis. This compound is crucial for researchers and manufacturers requiring a high-purity intermediate to construct complex molecules with precision. It is primarily sought after by the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery, ligand synthesis, and material science research.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly in constructing complex heterocycles or as a coupling partner in metal-catalyzed reactions.
• Agrochemical Research: Used in the development and synthesis of novel herbicides, fungicides, and plant growth regulators, leveraging its halogenated aromatic structure.
• Ligand & Catalyst Development: Acts as a starting material for synthesizing specialized ligands used in transition metal catalysis, such as palladium-catalyzed cross-coupling reactions.
• Material Science: Employed in the research of organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors, where its structure can influence charge transport properties.
• Chemical Synthesis Building Block: Provides a functionalized arene for further derivatization, such as Suzuki, Stille, or Sonogashira cross-coupling reactions, to create more complex molecular architectures.
• Academic & R&D Laboratories: Utilized in fundamental organic chemistry research and method development for new synthetic pathways.

Basic Information

Item	Detail
Product Name	5-Iodo-1,2,3-Trimethoxybenzene
CAS No.	25245-29-8
Molecular Formula	C9H11IO3
Molecular Weight	294.09 g/mol
Synonyms	1,2,3-Trimethoxy-5-iodobenzene; 3,4,5-Trimethoxyiodobenzene; 5-Iodo-1,2,3-trimethoxybenzene; 5-Iodopyrogallol trimethyl ether; Pyrogallol trimethyl ether, 5-iodo-
EINECS	Contact for details

Quality Control

Our 5-Iodo-1,2,3-Trimethoxybenzene is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.