Description

4-(Trifluoromethyl)Quinoline-2-Carbonitrile, 97% is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which combines a quinoline core with a trifluoromethyl group and a nitrile functionality, enabling precise structural modifications. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, as well as by material scientists exploring specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Serves as a versatile precursor in the design and synthesis of novel herbicides, fungicides, and insecticides, leveraging the stability imparted by the fluorine atoms.
• Material Science Research: Used in the development of advanced organic materials, including ligands for catalysis, organic semiconductors, and fluorescent dyes or probes.
• Chemical Biology: Employed as a molecular scaffold or tagging agent in probe development for studying biological processes and target identification.
• Custom Synthesis & Contract Manufacturing: An essential building block for custom chemical synthesis services catering to the needs of biotechnology and fine chemical companies.

Basic Information

Product Name	4-(Trifluoromethyl)Quinoline-2-Carbonitrile, 97%
CAS No.	25199-89-7
Molecular Formula	C11H5F3N2
Molecular Weight	222.17 g/mol
Synonyms	2-Cyano-4-(trifluoromethyl)quinoline; Quinoline-2-carbonitrile, 4-(trifluoromethyl)-; 4-(Trifluoromethyl)-2-quinolinecarbonitrile; 4-Trifluoromethylquinoline-2-carbonitrile; 2-Quinolinecarbonitrile, 4-(trifluoromethyl)-; 25199-89-7; 4-TFMQC
EINECS	Contact for details

Quality Control

Every batch of 4-(Trifluoromethyl)Quinoline-2-Carbonitrile, 97% is manufactured and tested under a strict quality management system. We ensure the identity, purity, and consistency of our products through advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing all specification results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.