Description

2-Chloro-3-(trifluoromethyl)quinoline is a versatile and high-value fluorinated quinoline derivative, serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both a chloro and a trifluoromethyl group on the quinoline scaffold, makes it an essential intermediate for creating compounds with tailored electronic and biological properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for antiviral, anticancer, and anti-inflammatory applications.
• Agrochemical Synthesis: Used to develop advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as OLEDs and semiconductors.
• Ligand and Catalyst Development: Employed in the design of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Studies: A valuable reagent for academic and industrial research focused on introducing trifluoromethyl groups into complex molecules.
• Dye and Pigment Intermediate: Can be utilized in the synthesis of specialized fluorinated dyes and pigments.

Basic Information

Product Name	2-Chloro-3-(trifluoromethyl)quinoline
CAS No.	25199-86-4
Molecular Formula	C₁₀H₅ClF₃N
Molecular Weight	231.60 g/mol
Synonyms	2-Chloro-3-(trifluoromethyl)quinoline; 3-Trifluoromethyl-2-chloroquinoline; 2-Chloro-3-trifluoromethylquinoline; Quinoline, 2-chloro-3-(trifluoromethyl)-; 25199-86-4; 2-Chloro-α,α,α-trifluoro-3-quinolinemethanol (precursor name); 2-Chloro-3-(trifluoromethyl)chinolin (German)
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Each batch of 2-Chloro-3-(trifluoromethyl)quinoline is analyzed using advanced techniques like HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. Our quality system is designed to support cGMP requirements for pharmaceutical development and meets the high standards demanded by global research and manufacturing partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider using an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.