Description

2-Amino-2-(2-Hydroxyphenyl)Acetic Acid is a multifunctional aromatic amino acid derivative that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its unique structure, featuring both amino and phenolic hydroxyl groups, makes it valuable for constructing complex molecules with specific stereochemistry and functionality. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and plant growth regulators that require specific stereoisomers for optimal activity.
• Ligand for Catalysis: Serves as a precursor for chiral ligands and catalysts used in asymmetric synthesis, enhancing enantioselectivity in critical reactions.
• Peptidomimetic Research: Incorporated into non-natural peptide analogs and peptidomimetics for biochemical and medicinal chemistry studies.
• Chelating Agent Precursor: Utilized to develop specialized chelating agents for metal ion sequestration or catalysis due to its phenolic and amino donor groups.
• Fine Chemical Building Block: Employed in the custom synthesis of dyes, pigments, and other performance chemicals requiring a bifunctional aromatic core.

Basic Information

Product Name	2-Amino-2-(2-Hydroxyphenyl)Acetic Acid
CAS No.	25178-38-5
Molecular Formula	C8H9NO3
Molecular Weight	167.16 g/mol
Synonyms	2-Amino(2-hydroxyphenyl)acetic acid; (2-Hydroxyphenyl)glycine; 2-Hydroxyphenylglycine; o-Hydroxyphenylglycine; 2-Amino-2-(2-hydroxyphenyl)ethanoic acid; Hpg; AT-125; NSC 163049
EINECS	Contact for details

Quality Control

Our 2-Amino-2-(2-Hydroxyphenyl)Acetic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support compliance with cGMP, ISO, and other relevant regulatory frameworks for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.