Description

(+)-Nicotine-(+)-Di-p-Toluoyl Tartrate CAS NO 25162-00-9 is a high-purity, enantiomerically pure salt derivative of nicotine, specifically designed for advanced research and development applications. This compound is critical for studies requiring precise stereochemical control, particularly in pharmacology and neuroscience. It serves as a key chiral intermediate and reference standard for academic institutions, pharmaceutical R&D laboratories, and agrochemical companies investigating nicotinic acetylcholine receptor (nAChR) interactions.

Application

• Pharmaceutical Reference Standard: Used as a high-purity calibrant and control substance in analytical method development and validation for nicotine and related alkaloid assays.
• Neuroscience Research: Essential for in-vitro and in-vivo studies targeting specific nicotinic acetylcholine receptor (nAChR) subtypes due to its defined stereochemistry.
• Chiral Intermediate: Serves as a building block in the synthetic pathways for novel chiral pharmaceuticals and bioactive compounds.
• Agrochemical Development: Employed in R&D for creating new generation, receptor-targeted plant protection agents and insecticides.
• Metabolite Studies: Utilized in pharmacokinetic and metabolic pathway research to understand the fate of nicotine derivatives in biological systems.
• Quality Control Laboratories: Acts a primary standard for ensuring the accuracy and precision of nicotine quantification in various sample matrices.

Basic Information

Product Name	(+)-Nicotine-(+)-Di-p-Toluoyl Tartrate
CAS No.	25162-00-9
Molecular Formula	C30H32N2O8
Molecular Weight	548.59 g/mol
Synonyms	(S)-Nicotine (S,S)-Di-p-Toluoyl Tartrate; (S)-Nicotine Di-p-Toluoyl-L-tartrate; L-Nicotine Di-p-Toluoyl-L-tartrate; Nicotine Ditoluoyltartrate; Nicotine DTTA Salt; (S)-(-)-Nicotine (2R,3R)-Di-p-Toluoyl Tartrate; Nicotine Hydrogen Di-p-Toluoyl Tartrate
EINECS	Contact for details

Quality Control

Our (+)-Nicotine-(+)-Di-p-Toluoyl Tartrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure identity, potency, and consistency. A detailed Certificate of Analysis (COA) providing full specifications and test results is supplied with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.