Description

(S)-1-(1-Phenylethyl)Urea is a high-purity chiral urea derivative characterized by its specific stereochemistry. This compound is a valuable chiral building block and resolving agent in asymmetric synthesis, offering critical control over stereochemical outcomes. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals where enantiomeric purity is paramount.

Application

• Chiral Auxiliary/Resolving Agent: Used for the resolution of racemic mixtures of acids, amines, and alcohols in pharmaceutical intermediate synthesis.
• Asymmetric Synthesis Building Block: Serves as a key precursor in the construction of complex molecules with defined stereocenters for drug discovery programs.
• Pharmaceutical Intermediate: Employed in the research and development of enantiomerically pure APIs, particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Research: Used in the synthesis of chiral herbicides, fungicides, and plant growth regulators to enhance efficacy and reduce environmental impact.
• Catalyst Ligand Precursor: Can be utilized to develop novel chiral ligands for transition metal catalysis.
• Academic & Process Chemistry: A standard reagent in university laboratories and process R&D for method development and scale-up studies.

Basic Information

Item	Details
Product Name	(S)-1-(1-Phenylethyl)Urea
CAS No.	25144-64-3
Molecular Formula	C9H12N2O
Molecular Weight	164.20 g/mol
Synonyms	(S)-(-)-1-Phenylethylurea; (S)-α-Methylbenzylurea; (S)-1-Phenylethylurea; Urea, N-[(1S)-1-phenylethyl]-; L-(-)-1-Phenylethylurea; (S)-PEU; (S)-N-(1-Phenylethyl)urea; (1S)-1-Phenylethylurea
EINECS	Contact for details

Quality Control

Our (S)-1-(1-Phenylethyl)Urea is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.