Description

1,2:4,5-Di-o-Isopropylidene-β-D-Fructopyranose is a protected sugar derivative, a key chiral intermediate in organic synthesis. Its value lies in providing a stable, non-reactive scaffold for the selective functionalization of the fructose molecule, enabling the production of complex, high-value compounds. This chemical is essential for research and manufacturing in the pharmaceutical and fine chemical industries, particularly for developing nucleoside analogs, antiviral agents, and other bioactive molecules. The compound is identified by CAS No. 25018-67-1.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of nucleoside analogs and antiviral drugs.
• Fine Chemical Synthesis: Used as a chiral precursor in the production of complex organic molecules and specialty chemicals.
• Carbohydrate Chemistry Research: Serves as a protected starting material for studying glycosylation reactions and sugar chemistry.
• Asymmetric Synthesis: Employed in the preparation of chiral catalysts and ligands due to its defined stereochemistry.
• Bioconjugate Chemistry: Utilized for linking sugars to other biomolecules like proteins or peptides in drug delivery research.
• Agrochemical Development: Acts as an intermediate in the synthesis of certain advanced, targeted agrochemicals.

Basic Information

Product Name	1,2:4,5-Di-o-Isopropylidene-β-D-Fructopyranose
CAS No.	25018-67-1
Molecular Formula	C12H20O6
Molecular Weight	260.28 g/mol
Synonyms	1,2:4,5-Di-O-isopropylidene-β-D-fructopyranose; Diacetone fructose; Diacetone-D-fructose; 1,2:4,5-Di-O-(1-methylethylidene)-β-D-fructopyranose; D-Fructose diacetone; 2,3:4,5-Di-O-isopropylidene-β-D-fructopyranose; D-Fructose 1,2:4,5-di-O-isopropylidene acetal; Isopropylidene fructose
EINECS	246-589-7

Quality Control

Our 1,2:4,5-Di-o-Isopropylidene-β-D-Fructopyranose is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing specifications such as assay, optical rotation, and impurity profiles. Our quality commitment supports applications requiring high-purity intermediates, including cGMP manufacturing for pharmaceuticals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Optical Rotation	-80° to -90° (c=1 in H2O)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.