Description

Trehalose Octaacetate is a fully acetylated derivative of the natural disaccharide trehalose, offering enhanced lipophilicity and stability. This chemical modification is critical for applications requiring a non-polar, protected form of trehalose that is soluble in organic solvents. It serves as a key intermediate and protective agent in advanced organic synthesis, particularly for the pharmaceutical, agrochemical, and specialty chemical industries seeking to leverage the unique properties of trehalose in novel formulations.

Application

• Pharmaceutical Intermediate: Used in the synthesis of prodrugs and active pharmaceutical ingredients (APIs) where the acetyl groups provide temporary protection for hydroxyl functionalities.
• Agrochemical Synthesis: Acts as a building block for developing novel, more lipophilic pesticide and herbicide formulations with improved delivery characteristics.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies, particularly those involving carbohydrate-active enzymes like esterases and lipases.
• Material Science: Serves as a precursor for creating specialty polymers, coatings, or dendrimers with specific solubility and degradation profiles.
• Flavor & Fragrance Industry: Can be used as a starting material for the synthesis of complex flavor compounds due to its sugar backbone and modifiable acetyl groups.
• Cosmetic Ingredient Intermediate: Utilized in the development of novel emollients or skin-conditioning agents that benefit from the moisturizing properties of trehalose derivatives.

Basic Information

Product Name	Trehalose Octaacetate
CAS No.	25018-27-3
Molecular Formula	C28H38O19
Molecular Weight	678.59 g/mol
Synonyms	α,α-Trehalose Octaacetate; D-(+)-Trehalose Octaacetate; OCTA-O-ACETYL-α,α-TREHALOSE; α-D-Glucopyranoside, α-D-glucopyranosyl, octaacetate; Trehalose Peracetate; 1,1'-Diacetyl-2,2',3,3',4,4',6,6'-octaacetyl-α,α-trehalose; NSC 2090; Trehalose Octa Acetate
EINECS	246-576-7

Quality Control

Our Trehalose Octaacetate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, optical rotation, and impurity profiles. We can support development and commercial projects requiring compliance with ICH guidelines and other relevant regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	+138° to +142° (c=1 in CHCl₃)
Melting Point	98°C - 102°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.