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9,10-Dihydro-9,10-Dihydroxybenzo(A)Pyrene CAS NO 24909-09-9
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CAS No.:24909-09-9
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
9,10-Dihydro-9,10-Dihydroxybenzo(A)Pyrene is a key dihydrodiol metabolite of benzo[a]pyrene, a well-studied polycyclic aromatic hydrocarbon (PAH). This compound is of significant interest in biochemical and toxicological research as a critical intermediate in the metabolic activation pathway of carcinogenic PAHs. It serves as an essential reference standard and analytical reagent for laboratories investigating environmental pollution, metabolic pathways, DNA adduct formation, and chemical carcinogenesis. The product is supplied with a CAS number of 24909-09-9.
Application
- Biochemical Research Standard: Used as a high-purity analytical standard for calibrating equipment and quantifying metabolites in complex biological matrices.
- Toxicology Studies: Critical for investigating the metabolic activation, detoxification, and carcinogenic mechanisms of benzo[a]pyrene and related PAHs.
- Environmental Analysis: Employed in method development and validation for detecting and monitoring PAH metabolites in environmental and occupational exposure samples.
- DNA Adduct Research: Serves as a precursor in studies examining the formation and repair of DNA adducts, which are critical events in chemical carcinogenesis.
- Enzymology Assays: Used as a substrate to study the activity and kinetics of cytochrome P450 enzymes and epoxide hydrolase involved in PAH metabolism.
- Pharmaceutical Intermediates: Potential use as a building block or reference compound in the development of chemopreventive agents or metabolic inhibitors.
Basic Information
| Product Name | 9,10-Dihydro-9,10-Dihydroxybenzo(A)Pyrene |
| CAS No. | 24909-09-9 |
| Molecular Formula | C₂₀H₁₄O₂ |
| Molecular Weight | 286.33 g/mol |
| Synonyms | 9,10-Dihydro-9,10-dihydroxybenzo[a]pyrene; Benzo[a]pyrene 9,10-dihydrodiol; BP 9,10-dihydrodiol; trans-9,10-Dihydroxy-9,10-dihydrobenzo[a]pyrene; (±)-trans-9,10-Dihydroxy-9,10-dihydrobenzo[a]pyrene; 9,10-Dihydroxy-9,10-dihydrobenzo[a]pyrene; Benzo[a]pyrene-9,10-diol |
| EINECS | Contact for details |
Quality Control
Our products undergo rigorous quality testing to ensure compliance with industry standards for research chemicals. Each batch is characterized using advanced analytical techniques to confirm identity and purity. Certificates of Analysis (COA) detailing specific test results are available upon request to support your research and regulatory documentation needs.
Storage
Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to prevent contamination and moisture absorption.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 95.0% |
| Melting Point | Contact for details |
| Water Content (KF) | ≤ 1.0% |
| Residue on Ignition | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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