Description

6Alpha-tert-Butyl-3,4,4Abeta,5,6,7,8,8Aalpha-Octahydronaphthalen-2(1H)-One CAS NO 24817-28-5 is a high-purity, sterically hindered bicyclic ketone that serves as a critical advanced intermediate in complex organic syntheses. Its unique decalin-based structure with a tert-butyl group provides exceptional stereochemical control and stability, making it invaluable for constructing intricate molecular architectures. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel therapeutic agents, including steroids, terpenoids, and other bioactive molecules.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and plant growth regulators requiring specific stereochemistry.
• Fine Chemical Production: Serves as a precursor for fragrances, flavors, and other high-value specialty chemicals where structural complexity is required.
• Material Science Research: Employed in the development of novel polymers, liquid crystals, and organic electronic materials due to its rigid, bulky structure.
• Catalyst & Ligand Development: Acts as a scaffold for creating sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry, particularly in reactions like hydrogenation, cyclization, and cross-coupling.

Basic Information

Product Name	6Alpha-tert-Butyl-3,4,4Abeta,5,6,7,8,8Aalpha-Octahydronaphthalen-2(1H)-One
CAS No.	24817-28-5
Molecular Formula	C₁₄H₂₄O
Molecular Weight	208.34 g/mol
Synonyms	6α-tert-Butylperhydronaphthalen-2-one; 6-tert-Butyldecalin-2-one; 2(1H)-Naphthalenone, octahydro-6-(1,1-dimethylethyl)-, (4aR,6S,8aS)-rel-; 6-tert-Butyl-1,2,3,4,4a,5,6,7,8,8a-decahydronaphthalen-2-one; 6-(tert-Butyl)decalin-2-one; 6-tert-Butyl-2-decalone; 6-tert-Butyl-2-oxodecalin; 6-tert-Butyloctahydronaphthalen-2(1H)-one
EINECS	Contact for details

Quality Control

Our 6Alpha-tert-Butyl-3,4,4Abeta,5,6,7,8,8Aalpha-Octahydronaphthalen-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical and isomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isomeric Purity (GC/HPLC)	≥ 97.0% (6α-tert-Butyl isomer)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.