Description

(23R,24R,25S)-23,24-Epoxy-5α-Spirostane CAS NO 24744-31-8 is a high-purity, steroidal sapogenin derivative characterized by its specific stereochemistry and epoxy functional group. This compound serves as a critical advanced intermediate in the synthesis of complex steroid-based pharmaceuticals and bioactive molecules. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in the fields of endocrinology and oncology.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of steroidal drugs and hormone analogs.
• Research & Development: Used in academic and industrial laboratories for studying steroid biosynthesis pathways and receptor interactions.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Employed in the investigation of enzyme inhibitors and modulators of steroidal metabolism.
• Fine Chemical Synthesis: Utilized as a precursor for creating novel spirostane derivatives with potential biological activity.

Basic Information

Product Name	(23R,24R,25S)-23,24-Epoxy-5α-Spirostane
CAS No.	24744-31-8
Molecular Formula	C27H42O4
Molecular Weight	430.62 g/mol
Synonyms	(23R,24R,25S)-23,24-Epoxy-5α-spirostan; 23,24-Epoxy-5α-spirostane; 5α-Spirostan-23,24-epoxide; (23R,24R,25S)-23,24-Epoxy-5α-spirostan-3β-ol (if referring to the 3β-ol derivative); Spirostan-23,24-epoxide; 24744-31-8; 23,24-Epoxyspirostane
EINECS	Contact for details

Quality Control

Our (23R,24R,25S)-23,24-Epoxy-5α-Spirostane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring compliance with research and pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.