Description

(14β,25R)-5α-Spirostan-3-One Ethylene Acetal is a high-purity, steroidal intermediate characterized by its specific stereochemistry at the 14β and 25R positions. This compound is a critical building block in the synthesis of complex steroid-based pharmaceuticals and bioactive molecules, where precise stereochemical control is paramount. It is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries working on novel therapeutic agents and plant growth regulators.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the multi-step synthesis of steroidal drugs, including potential cardiotonic agents, anti-inflammatory drugs, and hormone modulators.
• Agrochemical Research: Used in the development of novel plant growth regulators and eco-friendly pesticides that leverage steroidal pathways.
• Fine Chemical Synthesis: Serves as a versatile starting material for creating custom steroidal libraries and specialty chemicals for advanced material science.
• Biochemical Research: Employed in academic and industrial laboratories to study steroid biosynthesis, enzyme inhibition, and receptor-ligand interactions.
• Process Development: Utilized for scaling up and optimizing synthetic routes to complex natural products and their analogs.

Basic Information

Product Name	(14β,25R)-5α-Spirostan-3-One Ethylene Acetal
CAS No.	24742-86-7
Molecular Formula	C29H46O4
Molecular Weight	458.68 g/mol
Synonyms	5α-Spirostan-3-one, ethylene acetal, (14β,25R)-; (25R)-5α-Spirostan-3-one 3-ethylene acetal; Tigogenone ethylene acetal; (14β,25R)-Spirostan-3-one ethylene ketal; 3,20-Dioxo-5α,14β,25R-spirostan-3-ethylene acetal; Tigogenin-3-one ethylene acetal
EINECS	Contact for details

Quality Control

Our (14β,25R)-5α-Spirostan-3-One Ethylene Acetal is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% de (by Chiral HPLC)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity	≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.