Description

(25R)-5α-Spirost-14-Ene-3β,12α-Diol CAS NO 24742-82-3 is a high-purity steroidal sapogenin derivative, a key intermediate in the synthesis of complex bioactive molecules. Its defined stereochemistry and specific hydroxylation pattern make it a valuable building block for pharmaceutical research and development. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for the development of novel steroid-based therapeutics and reference standards.

Application

• Pharmaceutical Intermediate: A critical chiral precursor for the synthesis of steroid-based active pharmaceutical ingredients (APIs) and drug candidates.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Biochemical Research: Employed in studies investigating steroid biosynthesis pathways, enzyme inhibition, and receptor binding assays.
• Fine Chemical Synthesis: Serves as a versatile starting material for the semi-synthesis of other specialized steroidal compounds with modified biological activity.

Basic Information

Product Name	(25R)-5α-Spirost-14-Ene-3β,12α-Diol
CAS No.	24742-82-3
Molecular Formula	C27H42O4
Molecular Weight	430.62 g/mol
Synonyms	5α-Spirost-14-ene-3β,12α-diol; (25R)-Spirost-14-ene-3β,12α-diol; 12α-Hydroxytigogenin; Tigogenone; Tigogenin derivative; 3β,12α-Dihydroxy-5α-spirost-14-ene; 24742-82-3
EINECS	Contact for details

Quality Control

Our (25R)-5α-Spirost-14-Ene-3β,12α-Diol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the stringent requirements for research and synthesis applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.